Diltiazem

Known commericially as: cardizem , Tildiem


General information:

Dosage Form: Tab. 60 mg ,90 mg, 120 mg


Pregnancy: Avoid.
Indication: Angina | Mild to moderate hypertension
Interactions: Contraindicated (3)dantrolene , flibanserin , lomitapide⚠️⚠️ Serious - Use Alternative (72) • afatinib • alosetron • amisulpride • amlodipine • apalutamide • astemizole • atenolol • axitinib • betaxolol • bisoprolol • bosutinib • carbamazepine • cimetidine • cisapride • clonidine • cobimetinib • copanlisib • dihydroergotamine • dihydroergotamine intranasal • dronedarone • duloxetine • edoxaban • eliglustat • encorafenib • ergotamine • erythromycin base • erythromycin ethylsuccinate • erythromycin lactobionate • erythromycin stearate • esmolol • everolimus • fentanyl • fentanyl intranasal • fentanyl iontophoretic transdermal system • fentanyl transdermal • fentanyl transmucosal • idelalisib • itraconazole • ivabradine • ivacaftor • ivosidenib • ketoconazole • levobunolol • lofexidine • lovastatin • metoprolol • midostaurin • nadolol • naloxegol • nebivolol • nefazodone • neratinib • olaparib • pazopanib • pimozide • pomalidomide • propranolol • rifabutin • rifampin • riociguat • sertindole • silodosin • simvastatin • sirolimus • sotalol • st john's wort • terfenadine • timolol • tizanidine • tolvaptan • venetoclax • vilazodone
Side effects: SIDE-EFFECTS ▶️ Common or very common Abdominal pain . dizziness . fatigue . flushing . headache . nausea . oedema . palpitation . sleep disturbances ▶️ Uncommon Alopecia . arthralgia . asthenia . back pain . chest pain . dry mouth . dyspnoea . gastro-intestinal disturbances . gynaecomastia . hypotension . impotence . mood changes . muscle cramps . myalgia . paraesthesia . pruritus . purpura .rashes .rhinitis . skin discolouration . sweating . syncope .taste disturbances .tinnitus .tremor. urinary disturbances . visual disturbances . weight changes ▶️ Very rare Angioedema . arrhythmias . cholestasis . coughing . gastritis . gingival hyperplasia . hepatitis . hyperglycaemia . jaundice . myocardial infarction . pancreatitis . peripheral neuropathy .tachycardia . thrombocytopenia . urticaria . vasculitis

Mechanism:



Additional: